Inherited epigenetic variation--revisiting soft inheritance
Department of Biology, Washington University,
1 Brookings Drive, St Louis,
Missouri 63130, USA.
Nat Rev Genet. 2006 May;7(5):395-401.
ABSTRACTPhenotypic variation is traditionally parsed into components that are directed by genetic and environmental variation. The line between these two components is blurred by inherited epigenetic variation, which is potentially sensitive to environmental inputs. Chromatin and DNA methylation-based mechanisms mediate a semi-independent epigenetic inheritance system at the interface between genetic control and the environment. Should the existence of inherited epigenetic variation alter our thinking about evolutionary change?Private eugenics
Selecting potential children
Brain size/human evolution
Transhumanism/Brave New World?
Transgenerational epigenetic effects
Transgenerational epigenetic inheritance
Developmental and environmental variation in genomes
Maternal inheritance, epigenetics and the evolution of polyandry
and further reading
The Good Drug Guide
The Abolitionist Project
The Hedonistic Imperative
The Reproductive Revolution
MDMA: Utopian Pharmacology
Critique of Huxley's Brave New World